If you've been told you have prediabetes, you're not "doomed" — you're early. Prediabetes is a window where the right steps can lower blood sugar, improve insulin sensitivity, and reduce the chance of progressing to type 2 diabetes.
The most proven prediabetes treatments are lifestyle‑based:
- Modest weight loss (often ~5–7% of body weight) if you have overweight
- At least 150 minutes/week of moderate activity (like brisk walking)
- A structured behavior plan you can stick with (not a "perfect" diet for 2 weeks)
In a major clinical trial (the Diabetes Prevention Program), a structured lifestyle approach reduced progression to type 2 diabetes by 58%, and metformin reduced it by 31% compared to placebo.
Medical note: This article is educational and not medical advice. If you take glucose‑lowering medication or have other conditions, work with a licensed clinician before changing diet, exercise, or medications.
Quick Answer: Evidence‑Based Prediabetes Treatments
Prediabetes treatments that are most supported by evidence include:
- Structured lifestyle change (nutrition + activity + habits) aiming for ~5–7% weight loss and 150 minutes/week of activity
- Ongoing monitoring (often at least annually) to catch rising A1C/glucose early
- Medication in selected higher‑risk people, especially metformin, which ADA guidance says may be considered in certain high‑risk profiles
- Support systems that make the behavior change sustainable (coaching, community, tracking, meal planning, stress/sleep routines)
What Is Prediabetes?
Prediabetes is the term used when blood sugar is higher than normal but not high enough for a diabetes diagnosis. Common clinical criteria include:
- A1C 5.7–6.4%
- Fasting plasma glucose 100–125 mg/dL
- 2‑hour OGTT 140–199 mg/dL
Prediabetes matters because it's associated with a higher likelihood of developing type 2 diabetes and a higher cardiometabolic risk profile — which is why treatment focuses on more than just glucose numbers. For a deeper understanding of how blood sugar regulation works, see our guide on metabolic health fundamentals.
Prediabetes Treatments, Step 1: A Realistic Weight‑Loss Target
If you carry extra weight, a small reduction can move the needle significantly. CDC guidance commonly highlights ~5–7% weight loss (example: 10–14 pounds if you weigh 200 pounds).
This target is popular because:
- It's achievable without extreme measures for many people
- It's tied to improved glycemia and risk reduction in high‑quality research
How to Apply This Without "Diet Brain"
- Focus on consistency, not perfection
- Build meals that keep you full (fiber + protein + minimally processed carbs)
- Use weekly trends (weight, steps, meal consistency) instead of daily all‑or‑nothing thinking
Prediabetes Treatments, Step 2: Nutrition Changes That Lower Glucose Swings
There isn't one "best" prediabetes diet for everyone. The common thread across effective approaches is improving food quality, portion patterns, and carbohydrate quality so blood sugar spikes are smaller and less frequent. Our nutrition science resources offer deeper guidance on evidence-based eating patterns.
A Simple Plate Strategy (Works for Most People)
Aim for most meals to include:
- Non‑starchy vegetables (fiber + volume)
- Protein (helps satiety and reduces post‑meal glucose rise)
- High‑fiber carbohydrates in portions that match your body (beans, lentils, intact whole grains, fruit)
- Healthy fats in reasonable portions (olive oil, nuts, seeds, avocado)
High‑Impact Swaps (Easier Than "Starting Over")
| Instead of... | Try... |
|---|---|
| Sugary drinks | Water, unsweetened tea, sparkling water |
| Refined snacks | Nuts, Greek yogurt, fruit + nut butter, hummus + veggies |
| Oversized carb portions | Slightly smaller carb serving + more vegetables + protein |
| Late‑night grazing | A planned evening snack (if needed) + a "kitchen closed" habit |
Prediabetes Treatments, Step 3: The Activity Dose That's Been Studied
Regular movement improves insulin sensitivity and helps muscles use glucose.
CDC's Widely Cited Target
At least 150 minutes/week of moderate activity (ex: brisk walking) — often framed as 30 minutes/day, 5 days/week. The CDC's National Diabetes Prevention Program uses this as a cornerstone recommendation.
Make It Sustainable (Instead of Intimidating)
- Start with 10 minutes after meals (breakfast/lunch/dinner)
- Add 2 days/week of resistance training (bodyweight, bands, weights)
- Reduce long sitting stretches (short walks, stairs, "movement snacks")
If your schedule is chaotic, remember: consistency beats intensity. You're building a metabolism‑supportive lifestyle, not training for a race.
Prediabetes Treatments, Step 4: Join a Structured Lifestyle Program
If you've ever tried to "just be disciplined" and watched it fade by week 3, you're not alone. Structure helps.
The CDC's National Diabetes Prevention Program (National DPP) is a year‑long lifestyle change program designed to help people at risk make lasting changes (nutrition, activity, coping skills). It's built on research including the Diabetes Prevention Program trial.
In research underlying these programs, people who achieved weight loss and activity goals saw major reductions in progression risk.
What to Look for in Any Program (In‑Person or Digital)
- Coaching + accountability
- Real‑life meal strategies (not "perfect meal plans" only)
- Progress tracking that doesn't trigger shame
- Support for stress, sleep, and habit change
This is where structured support programs like our Done With Diabetes Protocol can make the difference — combining evidence-based nutrition with sustainable behavior change strategies.
Prediabetes Treatments, Step 5: Monitoring and Follow‑Up
Prediabetes isn't a one‑and‑done label. It's a risk state that should be tracked.
ADA Standards of Care (2026) notes that people with prediabetes should be monitored for progression to diabetes at least annually, with frequency adjusted based on individual risk.
What to Track (With Your Clinician)
- A1C and/or fasting glucose
- Weight trend and waist circumference (if relevant)
- Blood pressure and cholesterol
- Sleep quality and stress load (yes, really)
Why it matters: Early changes are easier to reverse than late ones.
Prediabetes Treatments, Step 6: When Medications May Be Part of the Plan
Lifestyle is the foundation, but some people benefit from adding medication — especially if they're at higher risk or not seeing enough improvement.
Metformin for Prediabetes: Who May Consider It?
ADA Standards of Care (2026) says metformin for prevention of type 2 diabetes should be considered in adults at high risk, especially:
- Ages 25–59 years with BMI ≥35 kg/m²
- Higher fasting glucose (example ≥110 mg/dL)
- Higher A1C (example ≥6.0%)
- History of gestational diabetes
What Metformin Does (High Level)
- Improves insulin sensitivity
- Lowers glucose production in the liver
- Has evidence for reducing progression in prediabetes populations
Important nuance: Metformin is commonly used, but it may not be FDA‑labeled specifically for "prevention" in the U.S. — discuss risks/benefits with your clinician.
What About Newer Weight‑Loss Medications?
ADA notes that several drug classes (including GLP‑1–based therapies) have shown lower diabetes incidence in some populations, but emphasizes that long‑term data supporting pharmacologic treatments other than metformin solely for diabetes prevention are limited; however, using GLP‑1–based therapies for weight management can be highly beneficial and should be considered when appropriate.
This typically becomes relevant when:
- Weight is a major driver of insulin resistance
- Lifestyle changes alone aren't enough
- There are other cardiometabolic risks present
This is a clinician decision — not a DIY decision.
How Long Do Prediabetes Treatments Take to Work?
Some people notice changes (energy, cravings, post‑meal glucose trends) within weeks. Lab changes (like A1C) are usually assessed over a longer window because A1C reflects roughly the last ~3 months of glycemic exposure.
The bigger point: Prediabetes treatment is not a 30‑day challenge — it's a system.
In long‑term follow‑up of DPP participants, lifestyle intervention and metformin continued to show reduced diabetes incidence compared with placebo over many years (though differences changed over time).
Common Myths About Prediabetes Treatments
Myth 1: "I just need to cut sugar."
Reducing added sugar helps, but what matters most is your overall pattern: total food quality, portion consistency, activity, and sleep/stress.
Myth 2: "If my numbers improve, I'm cured forever."
Prediabetes can improve — sometimes into normal ranges — but the underlying tendency (insulin resistance) can return if old patterns return. Ongoing habits are the "treatment."
Myth 3: "Supplements replace lifestyle."
Supplements may have niche roles, but they are not a substitute for the core treatments with strong evidence.
A Simple 4‑Week Prediabetes Treatment Plan Starter
Week 1: Build Awareness
- Track 1–2 meals/day (no judgment)
- Walk 10 minutes after one meal each day
- Pick one "high sugar" item to swap (ex: soda)
Week 2: Lock in a Routine
- Walk 10 minutes after two meals/day
- Add a protein‑forward breakfast 4 days/week
- Choose a consistent grocery list
Week 3: Add Strength
- Add 2 short strength sessions (15–25 min)
- Increase non‑starchy veggies at lunch/dinner
- Set a sleep "anchor" time (wake or bedtime)
Week 4: Add Structure
- Consider a structured lifestyle program (coach + accountability)
- Schedule follow‑up labs and a clinician check‑in
- Create an "if‑then" plan for weekends/social events
When you're ready to take the next step, explore our Done With Diabetes Program or Start Program to get personalized support.
When to Talk to a Clinician Sooner
Get medical guidance promptly if:
- You're pregnant (or planning pregnancy)
- You have symptoms of high blood sugar (excess thirst/urination, unexplained weight loss, blurry vision)
- You take medications that affect glucose
- You're considering medication (metformin or weight‑loss pharmacotherapy)
The U.S. Preventive Services Task Force (USPSTF) recommends that clinicians screen eligible adults and offer or refer those with prediabetes to effective preventive interventions.
Frequently Asked Questions
Can prediabetes be reversed?
Many people can return blood sugar to a normal range with lifestyle changes. The key is maintaining the habits that produced the improvement and continuing follow‑up monitoring.
What's the best treatment for prediabetes?
The most evidence‑supported approach is a structured lifestyle change program (nutrition + activity + behavior support) aiming for modest weight loss and regular movement.
Do I need metformin for prediabetes?
Not everyone. ADA guidance suggests considering metformin in higher‑risk adults (specific age/BMI/glucose/A1C profiles and history of gestational diabetes).
How often should I retest?
Guidance commonly suggests at least annual monitoring for people with prediabetes, adjusted based on risk.
What is the prediabetes A1C range?
Prediabetes is typically defined as an A1C between 5.7% and 6.4%. An A1C of 6.5% or higher on two separate tests indicates diabetes.
How does prediabetes affect my heart health?
Prediabetes is associated with increased cardiovascular risk even before progressing to diabetes. This is why treatment focuses on overall metabolic health — including blood pressure, cholesterol, and inflammation — not just glucose numbers.
References
- ADA Standards of Care in Diabetes—2026 (Prediabetes prevention/delay; metformin criteria; monitoring)
- CDC National Diabetes Prevention Program
- U.S. Preventive Services Task Force: Prediabetes and Type 2 Diabetes Screening
- Diabetes Prevention Program Research Group. Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications.
Last reviewed: January 2026